Seeing how we are currently in an era of remakes and reboots, what gaming classic would you like to see rebooted/remade with current/next-gen graphics?
Chrono Trigger, Final Fantasy VI, and Super Castlevania IV. Keep the game play the same but amp up the graphics to look like Odin Sphere or Dragons Crown. And FFVII with graphics on par with FFXIII would be pretty cool too. As for reboots Contra, Battletoads, and Alundra.
Onimusha reboot and a panzer dragoon saga remake.
A sequal to Psychonauts...
Tactics Ogre or Final Fantasy Tactics a console remake or a new game altogether with HD but console not handheld.
They remade FFT again for iOS with HD graphics already, plus those saw ports on the PsP. What they really need is a sequel to the original FFT. 
No i want a console remake but a sequel to either would be bad ass just no more handheld ports i want a full blown console remake in HD yea!!!
FFVI, Illusion of Gaia trilogy, Sonic CD, MAJORA'S MASK!!, Snatcher and Policenaughts, Sin and Punishment. On the tip of my tonuge, i'll ad more below.
Star Fox, Psychonauts, Beyond Good & Evil, and Street Sharks, based on the TV show of the same name.
Final Fantasy VI or VII. 
Blaster Master - Full Reboot, no sequel. And they should change the name to S.O.P.H.I.A. and make the truck semi sentient.
I second Snatcher/Policenauts. Kojima needs to STOP MILKING MGS
Shinobi. Even if its a HD remake of Revenge of Shinobi on XBLA
STRIDER
I really want a remake of FF9, I want the graphics to look like the newer final fantasy titles and the characters to have voices. Thats all though, dont want anything changed about the story.
I'd remake this hot ass summer into a cool ass spring. 
Elite. Ye Olde PC Space Game.
Star Wars: Knights of the Old Republic
I wouldn't mind a remake of Brave Fencer Musashi. I also second Contra. We got Uprising which was awesome, but it really didn't feel like a Contra game.
Ultima 7, System Shock 2 remakes, reboot Legend of Zelda that is more in line with the first two games.
Super star wars as a platformer still but with some serious HD treatment.
How about Beyond Dark Castle. It's a 2D side-scrolling action game that came out for Apple Macintosh back in the late eighties. I played it a lot in college. It could be redone in color with some new levels for all the download services: XBLA, PSN, and iOS. It would be just like The Cave with its gorgeous graphics, puzzle solving, platforming, and exploration but with more action.
The original Zork, but with graphics! That would be amazing!
I may be the only one who says this but I'd love to see Paper Boy and Smash Tv remade, that would be cool.
Mega Man. It's nice with the last two being a retro look but why not give it a next gen go like they did with Mega Man 7 on the SNES?
What? Stop looking at me like that!